GLP-1s
Discover the Power of GLP-1s
GLP-1 receptor agonists are a class of medications that replicate the function of a naturally occurring hormone in the body: glucagon-like peptide-1.
Unlike supplements, GLP-1 medications contain synthetic or bioengineered versions of hormones that naturally occur in the body. These active compounds are designed to bind to GLP-1 receptors in the brain and digestive tract.
Most GLP-1 medications use modified peptides that resist breakdown in the body, allowing them to stay active longer and require only once-daily or once-weekly dosing.
There are several types of GLP-1 medication ingredients currently in use. These differ by duration of action, molecular structure, and mechanism of action. Here are the primary types:
1. Short-Acting GLP-1 Receptor Agonists
These medications are typically administered once or twice daily. They primarily target post-meal blood sugar spikes by slowing gastric emptying and enhancing insulin response shortly after eating.
2. Long-Acting GLP-1 Receptor Agonists
Designed for once-weekly use, long-acting formulations maintain a more consistent presence in the bloodstream, providing steady appetite regulation and improved insulin sensitivity throughout the week.
3. Dual or Multi-Agonists (GLP-1 + GIP or GLP-1 + Glucagon)
This treatment stimulates multiple metabolic hormone receptors at once, such as GIP (glucose-dependent insulinotropic polypeptide) in addition to GLP-1.
It is important to remember that GLP-1 medications are only available by prescription from a licensed medical provider. Your provider will determine whether a GLP-1 product is right for you.
The content on this website is for informational purposes only and is not a substitute for professional medical advice.
GLP-1 therapies are powerful and should only be used under the guidance of a licensed medical provider. They are not appropriate for everyone.
Do not use GLP-1s if you:
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Have a personal or family history of certain types of thyroid cancer (e.g., medullary thyroid carcinoma) or multiple endocrine neoplasia type 2
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Have had pancreatitis or gallbladder disease unless cleared by your doctor
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Are pregnant, planning to become pregnant, or breastfeeding
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Have severe gastrointestinal disease (consult your healthcare provider)
Common side effects may include:
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Nausea, especially during the first few weeks
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Constipation or diarrhea
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Fatigue or low energy
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Mild stomach cramping
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Temporary decrease in appetite
To reduce side effects, your provider will typically start with a low dose and increase gradually. Staying hydrated and eating smaller meals can also help minimize discomfort.